Exacerbations of chronic obstructive pulmonary disease and chronic mucus hypersecretion

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Chronic Obstructive Pulmonary Disease Exacerbations

INTRODUCTION Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States, accounting for approximately 110,000 deaths per year. COPD is a slowly progressive condition, with symptoms typically arising around age 50 to 60 years. As the U.S. population of current and former smokers ages, the prevalence of this disease is expected to climb [1]. More than 1...

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Acute exacerbations of chronic obstructive pulmonary disease.

Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined by modification of the usual COPD symptoms, dyspnea, coughing and sputum, beyond daily variations, with a sudden onset, and requiring modification of the usual treatment. Exacerbations stud the course of COPD. Their frequency is variable, averaging 1-2 per year. Their frequency generally increases with COPD severity. ...

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Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a disease which is characterized by airway inflammation and progressive airflow limitation with poor reversibility. Patients with COPD can experience periods of acute deterioration, which are called exacerbations. There are different definitions for an acute exacerbation of COPD (AECOPD). A symptom reported AECOPD is defined solely based on a pati...

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Exacerbations of chronic obstructive pulmonary disease (COPD) cause morbidity, hospital admissions, and mortality, and strongly influence health-related quality of life. Some patients are prone to frequent exacerbations, which are associated with considerable physiologic deterioration and increased airway inflammation. About half of COPD exacerbations are caused or triggered primarily by bacter...

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The diagnosis and treatment of acute exacerbations (AEs) of chronic obstructive pulmonary disease (COPD) is controversial. In this section, we review (1) the epidemiology of this condition; (2) the etiology--many patients with AECOPD are thought to have a combination of viral and bacterial infections, which contribute to their exacerbation. Bacterial organisms are isolated more commonly after v...

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ژورنال

عنوان ژورنال: Clinical and Applied Immunology Reviews

سال: 2006

ISSN: 1529-1049

DOI: 10.1016/j.cair.2006.02.001